Are you physically dependent on opioids? Do you have symptoms when you try to stop using? This clinical research study at the Johns Hopkins Bayview Campus involves supervised opioid withdrawal in a residential setting. The goal of the study is to examine a sleep medication that might lessen the symptoms of opioid withdrawal. You must have opioid use disorder and be 18 or older to participate. Participation requires an inpatient stay of 11 days (10 nights) and 1 follow-up visit. Duration of the study is about 3 weeks. Compensation up to $1460 may be provided. Call (410) 550-1206 or email [email protected]. PI: Andrew Huhn, Ph.D. Protocol # IRB00198426